What’s the study about?
By studying the DNA (genetic material) that can be found in a saliva sample, these researchers hope to learn how known risk factors, such as hormone replacement therapy or other types of estrogen exposure, affect breast cancer risk for women who have their biomarkers.
If you enroll in this study, you will NOT receive any individual genetic results. Every participant is assigned an anonymous study number, and no information is connected to a name. This means that there is no way for the researcher to ever tell you anything about your results. By taking part in this study you will be helping researchers identify and learn more about the impact of hormones on women with certain biomarkers that could help prevent and treat breast cancer in the future.
If you sign up for the study “Hormones, the KRAS-variant, and Breast Cancer Risk”, the research team will contact you to confirm that you are eligible. If you decide to participate in the study, you will be asked to do the following:
• Sign and initial the consent form.
• Obtain a copy of the pathology report of your breast cancer if possible.
• Complete a questionnaire about your breast cancer and about yourself.
• Provide a saliva sample. The research team will mail you a saliva collection kit that will include a special container and instructions about how to collect your sample and send it back to the research team (at no cost to you).
Who is conducting the study?
Joanne Weidhaas, MD, PhD, Yale University, New Haven, Connecticut
Anywhere in the United States; all necessary participation is handled through the U.S. mail.
Who can participate?
You can sign up for “Hormones, the KRAS-variant, and Breast Cancer Risk” if you meet ALL of these MAIN criteria:
• You are a woman over the age of 18.
• You have been diagnosed with breast cancer at some point in your life (including DCIS and Stages I-IV).
• You are able to provide a saliva sample.
• You live in the United States
After you RSVP, the research team will contact you to ask additional questions to be sure that this study is a good fit for you.