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Your Saliva Can Help Researchers Learn How To Prevent Breast CAncer

We need women ANYWHERE in the United States who have had breast cancer at any point in their lives to participate in a study investigating the effects of hormone replacement therapy and other types of estrogen exposure on a marker of breast cancer risk.

Saliva samples contain biomarkers—biological markers than can indicate whether or not you have a disease or are likely to develop one. Biological markers also can be used to predict whether a tumor will respond to certain cancer treatments. A research team at Yale University has identified biomarkers that can be used to assess breast cancer risk. The team wants to learn more about how hormones affect the risk of developing breast cancer for women who have these biomarkers.

Please read on to learn more about what’s involved and who can participate. If this study isn’t right for you, please pass it on!

What’s the study about?

By studying the DNA (genetic material) that can be found in a saliva sample, these researchers hope to learn how known risk factors, such as hormone replacement therapy or other types of estrogen exposure, affect breast cancer risk for women who have their biomarkers.

If you enroll in this study, you will NOT receive any individual genetic results. Every participant is assigned an anonymous study number, and no information is connected to a name. This means that there is no way for the researcher to ever tell you anything about your results. By taking part in this study you will be helping researchers identify and learn more about the impact of hormones on women with certain biomarkers that could help prevent and treat breast cancer in the future.

What’s involved?

If you sign up for the study “Hormones, the KRAS-variant, and Breast Cancer Risk”, the research team will contact you to confirm that you are eligible. If you decide to participate in the study, you will be asked to do the following:

• Sign and initial the consent form.
• Obtain a copy of the pathology report of your breast cancer if possible.
• Complete a questionnaire about your breast cancer and about yourself.
• Provide a saliva sample. The research team will mail you a saliva collection kit that will include a special container and instructions about how to collect your sample and send it back to the research team (at no cost to you).

Who is conducting the study?

Joanne Weidhaas, MD, PhD, Yale University, New Haven, Connecticut

Where?

Anywhere in the United States; all necessary participation is handled through the U.S. mail.

Who can participate?

You can sign up for “Hormones, the KRAS-variant, and Breast Cancer Risk” if you meet ALL of these MAIN criteria:

• You are a woman over the age of 18.
• You have been diagnosed with breast cancer at some point in your life (including DCIS and Stages I-IV).
• You are able to provide a saliva sample.
• You live in the United States

After you RSVP, the research team will contact you to ask additional questions to be sure that this study is a good fit for you.

YES, SIGN ME UPYes, Sign Me Up

NO, THANKSNo Thanks

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Nola said...

Is anyone bothered that this study is for Mira dx? They are a private, for-profit firm that charges women lots of $$ to test for a genetic marker that increases the odds of breast and ovarian cancer. Organizations like Breast Cancer Action are currently fighting against companies that own our genes (like Myriad). Why is AOW proving access to thousands of free volunteers when Mira dx will turn around and charge us, and others like us, for the right to know whether we have this genetic marker?

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